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COMPOSITION TEVERELIX-TFA RECONSTITUABLE
专利权人:
Antev Limited
发明人:
申请号:
EP18181931.9
公开号:
EP3590524A1
申请日:
2018.07.05
申请国别(地区):
EP
年份:
2020
代理人:
摘要:
The present invention relates to a reconstitutable teverelix-TFA composition having a predefined molar ratio of teverelix to trifluoroacetate which is below the molar ratio required for microcrystal formation. Said composition remains stable during storage e.g. at a temperature around 2-8°C. Upon reconstitution a fixed amount of trifluoroacetate can be added to said composition thereby effectively and simply achieving an exact and desired molar ratio in order to obtain a fluid, milky microcrystalline aqueous teverelix-TFA suspension.
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