The Trustees of Columbia University in the City of New York
发明人:
STOCKWELL, Brent R.,SKOUTA, Rachid,DIXON, Scott
申请号:
EP14867950
公开号:
EP3076962A4
申请日:
2014.12.01
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
The present invention provides, inter alia, a compound having the structure of Formula (I). Also provided are compositions containing a pharmaceutically acceptable carrier and a compound according to the present invention. Further provided are methods for treating or ameliorating the effects of an excitotoxic disorder in a subject, methods of modulating ferroptosis in a subject, methods of reducing reactive oxygen species (ROS) in a cell, and methods for treating or ameliorating the effects of a neurodegenerative disease.