Johannes L. Zakrzewski,Marcel R.m. Van Den Brink,Michel Sadelain
申请号:
US16419865
公开号:
US20190307800A1
申请日:
2019.05.22
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The inventive subject matter relates to methods for treating a T-cell deficiency in a subject in need thereof, comprising administering to said subject a T-cell precursor isolated from an allogeneic donor, provided that said allogeneic donor is not MHC-matched to said subject. The inventive methods can be further enhanced by genetic engineering for targeted immunotherapy.