FATHEREE, PAUL R.,TURNER, S. DEREK,GOLDBLUM, ADAM,CHAO, ROBERT,GENOV, DANIEL
申请号:
CA2603654
公开号:
CA2603654C
申请日:
2006.04.05
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
The invention provides a crystalline hydrochloride salt of 1-isopropyl-2-oxo-1,2-dihydroquinoline-3-carboxylic acid {(1S,3R,5R)-8-[(R)-2-hydroxy-3-(methanesulfonyl-methyl-amino)propyl]-8-azabicyclo[3.2.1]oct-3-yl}amide or asolvate thereof. The invention also provides pharmaceutical compositionscomprising such crystalline salt forms, methods of using such crystalline saltforms to treat diseases associated with 5 HT4 receptor activity, and processesuseful for preparing such crystalline salt forms.