Открытое акционерное общество "Химико-фармацевтический комбинат "АКРИХИН" (ОАО "АКРИХИН") (RU)
发明人:
Тарасова Элина Николаевна (RU),Савельева Ольга Дмитриевна (RU),Питькин Андрей Сергеевич (RU),Алёшина Елена Юрьевна (RU)
申请号：
RU2013105187/15
公开号：
RU2013105187A
申请日:
2013.02.07
申请国别(地区):
RU
年份:
2014
代理人:
摘要：
1. Antibacterial pharmaceutical composition as a solid dosage form comprising as active ingredient moxifloxacin hydrochloride in a therapeutically effective amount and as auxiliary ingredients silicon dioxide, sodium croscarmellose, filler and lubricant, and not containing laktozu.2. A pharmaceutical composition according to claim 1, characterized in that it comprises moxifloxacin hydrochloride, which no peak 168.1 ppm in C-NMR spectrum or a line at an angle 2θ, equal to 26.7 in X-ray difraktogramme.3. A pharmaceutical composition according to claim 2, characterized in that it comprises moxifloxacin hydrochloride, which is characterized in that in C-NMR spectrum has a peak at 166.3 ppm and X-ray diffraction line is at an angle 2θ = 26,4 and 2θ = 26,98.4. A pharmaceutical composition according to claim 2, characterized in that it contains as anhydrous moxifloxacin hydrochloride Moxifloxacin gidrohlorid5. A pharmaceutical composition according to claim 4, characterized in that it comprises moxifloxacin hydrochloride as moxifloxacin, in which the X-ray diffraction pattern has the following lines at the angle 2θ, equal to 5.8, 8.6, 10,2.6. A pharmaceutical composition according to claim 2, characterized in that it is made in the form of tablets, coated obolochkoy.7. A pharmaceutical composition according to claim 6, characterized in that the shell is made based gidroksipropilmetiltsellyulozy.8. A pharmaceutical composition according to claim 7, characterized in that as filler microcrystalline tsellyuloza.9 used. A process for preparing a pharmaceutical composition according to any one of claims 1-9, in which the mixture of powders moxifloxacin1. Антибактериальная фармацевтическая композиция в виде твердой лекарственной формы, включающая в качестве действующего вещества моксифлоксацина гидрохлорид в терапевтически эффективном количестве, и в качестве вспомогательных ингредиентов диоксид кремния, кроскармеллозу натрия, наполнитель и лубрикант, и не содержащая лактозу.2. Ф
