CHILDRENS MEDICAL CENTER CORPORATION;CHILDREN'S MEDICAL CENTER CORPORATION
发明人:
ALT, FREDERICK,CHENG, HWEI-LING,TIAN, MING
申请号:
CA2936976
公开号:
CA2936976A1
申请日:
2015.01.23
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
Described herein are compositions (e.g. cells and transgenic animals) and methods relating to engineered Ig loci that permit expression of particular antibodies or antibody segments while still permitting recombination and/or maturation process for antibody optimization.