Harald Duerr,Frank Herting,Christian Klein,Joerg Thomas Regula,Matthias Rueth,Kay-Gunnar Stubenrauch
申请号：
US15603259
公开号：
US10683345B2
申请日:
2017.05.23
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention relates to bispecific antibody against human vascular endothelial growth factor (VEGF/VEGF-A) and against human angiopoietin-2 (ANG-2) of human IgG1 or IgG4 subclass with mutations I253A, H310A, and H435A, methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
