The present invention relates to a method for determining the permeation characteristics of a hollow fiber membrane. The permeation characteristics of the hollow fiber membrane are determined on a hollow fiber membrane bundle, and the hollow fiber membrane bundle is introduced into a housing to form a hollow fiber membrane bundle. A hollow fiber membrane whose end is opened at the first end of the hollow fiber membrane, and a hollow fiber membrane whose end is closed at the second end of the bundle of hollow fiber membranes. More particularly, the present invention relates to a method for determining the clearance of a hollow fiber membrane, more particularly a diffusive clearance. [Selection] Figure 1本発明は、中空糸膜の透過特性を決定する方法に関し、中空糸膜の透過特性は、中空糸膜束上で決定され、該中空糸膜束が、ハウジングに導入されて、中空糸膜束の第1の端部にて末端が開口された中空糸膜と、中空糸膜束の第2の端部にて末端が閉鎖された中空糸膜とを備える。より詳細には、本発明は、中空糸膜のクリアランス、より詳細には拡散性クリアランス決定する方法に関する。【選択図】図1