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Transmucosal formulation of compounds providing dihydroartemesinin for use in the treatment of Lyme disease
专利权人:
LONDONPHARMA LIMITED
发明人:
CALVIN JOHN ROSS
申请号:
GB201115179
公开号:
GB2482615B
申请日:
2009.04.23
申请国别(地区):
GB
年份:
2012
代理人:
摘要:
Pharmaceutical compositions for the treatment of Lyme disease (Borreliosis) comprising compounds capable of providing dihydroartemesinin and a pharmaceutically acceptable excipient formulated for transmucosal sublingual, buccal or nasal delivery, especially by a spray. The pharmaceutically acceptable excipient is selected from selected from medium/short chain triglycerides, omega-3-marine triglycerides and fish oil, rich in omega-3 acids. The preferred compound capable of providing dihydroartemesinin is artemether. The composition may further comprise an essential oil such as Levomenthol. Also provided are delivery devices containing the compositions.
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