Indiana University Research and Technology Corporation
发明人:
Paczesny Sophie
申请号:
US201615571954
公开号:
US2018139937(A1)
申请日:
2016.05.06
申请国别(地区):
美国
年份:
2018
代理人:
摘要:
Cell culture systems for producing IL-33 induced T9 cells and methods of using the IL-33 induced T9 cells (T9IL-33 cells) in a cell therapy for increasing anti-tumoral activity following allogeneic hematopoietic cell transplantation (HCT) and/or treating graft-versus-host disease (GVHD) are disclosed herein. Further, methods of using the T9IL-33 cells, alone or in combination with allogeneic hematopoietic cell transplantation, are described herein for cancer treatment.