An interferon composition is provided for enhancing the platelet count, reducing the recurrence rate of hepatitis, and/or improving the social function of hepatitis patients. The method comprises administering a low dose of IFN (about 5 IU to about 2500 IU of IFN-alpha) to a patient in need thereof. In one embodiment the IFN is alpha IFN or beta IFN, and more particularly, in one embodiment the administered biologically active IFN is human alpha IFN.本發明提供一種干擾素組合物,其用於提高血小板計數、降低肝炎復發率及/或改良肝炎患者之社會功能。方法包含向有需要之患者投與低劑量IFN(約5IU至約2500IU IFN-α)。在一個實施例中,該IFN係α IFN或β IFN,且更具體而言,在一個實施例中,該所投與之生物活性IFN係人類α IFN。