IMPLANTABLE SYSTEMS AND METHODS FOR USE THEREWITH FOR MONITORING AND MODIFYING ARTERIAL BLOOD PRESSURE WITHOUT REQUIRING AN INTRAVASCULAR PRESSURE TRANSDUCER
Brian Jeffrey Wenzel,Michael E. Benser,Taraneh Ghaffari Farazi,Timothy A. Fayram,Edward Karst,Allen Keel,Wenbo Hou,Jong Gill
申请号:
US13033484
公开号:
US20120215275A1
申请日:
2011.02.23
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Embodiments of the present invention are directed to implantable systems, and methods for use therewith, that monitor and modify a patients arterial blood pressure without requiring an intravascular pressure transducer. In accordance with an embodiment, for each of a plurality of periods of time, there is a determination one or more metrics indicative of pulse arrival time (PAT), each of which are indicative of how long it takes for the left ventricle to generate a pressure pulsation that travels from the patients aorta to a location remote from the patients aorta. Based on the one or more metrics indicative of PAT, the patients arterial blood pressure is estimated. Changes in the arterial blood pressure are monitored over time. Additionally, the patients arterial blood pressure can be modified by initiating and/or adjusting pacing and/or other therapy based on the estimates of the patients arterial blood pressure and/or monitored changes therein.