IMIDAZO(1,2-b)PYRIDAZINE DERIVATIVES AS KINASE INHIBITORS

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专利权人:

Daiichi Sankyo Co.; Ltd.

发明人:

TAKEDA Yasuyuki,TAKEDA Yasuyuki,YOSHIKAWA Kenji,YOSHIKAWA Kenji,KAGOSHIMA Yoshiko,KAGOSHIMA Yoshiko,YAMAMOTO Yuko,YAMAMOTO Yuko,TANAKA Ryoichi,TANAKA Ryoichi,TOMINAGA Yuichi,TOMINAGA Yuichi,KIGA Masak

申请号：

SI201330798

公开号：

SI2857404T1

申请日:

2013.06.03

申请国别(地区):

SI

年份:

2017

代理人:

摘要：

The present invention is intended to provide a compound or a pharmacologically acceptable salt thereof which is useful in the treatment of a tumor through its ROS1 kinase enzyme activity inhibitory effect and NTRK kinase enzyme inhibitory effect. The present invention provides a compound having an imidazo[1,2-b]pyridazine structure represented by the general formula (I) or a pharmacologically acceptable salt thereof, and a pharmaceutical composition comprising the compound. In the formula, R 1 , G, T, Y 1 , Y 2 , Y 3 , and Y 4 are as defined herein.

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中国工程科技知识中心

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http://www.ckcest.cn/home/