Hyuncheol Kim,Hyungwon Moon,Tai-Kyong Song,Jin Ho Chang,Yang Mo Yoo
申请号：
US14437816
公开号：
US20150343079A1
申请日:
2013.09.27
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The present invention relates to an ultrasound contrast agent with drug-encapsulating nanoparticles and a method for preparing the same that increase drug delivery capabilities and drug penetration effects. According to the present invention, exposure to the focussed ultrasound triggers the cavitation of an ultrasound contrast agent, resulting in the local release of drug-encapsulating nanoparticles, which are conjugated onto the surface of the ultrasound contrast agent, and enhanced penetration of nanoparticles and drug delivery capabilities. Moreover, the present invention simultaneously and selectively diagnoses and treats cancers by conjugation cancer-targeting ligands on the surface of nanoparticles.
