It is disclosed a method for the treatment of HBV infection or HBV/HDV co-infection, the method comprising administering to a subject in need of treatment a first pharmaceutically acceptable agent that removes the hepatitis B surface antigen from the blood and a second pharmaceutically acceptable agent which stimulates immune function.本發明揭示一種治療HBV感染或HBV/HDV合併感染之方法,該方法包含投與需要治療之個體自血液移除B型肝炎表面抗原之第一醫藥學上可接受之藥劑及刺激免疫功能之第二醫藥學上可接受之藥劑。