ZEENATHUL NAZARIAH BT. ALLAUDIN,TAN SEOK SHIN,MOHD AZMI MOHD LILA,NOORDIN BIN MOHAMED MUSTAPHA
申请号：
MYPI 2010001493
公开号：
MY160235A
申请日:
2010.04.02
申请国别(地区):
MY
年份:
2017
代理人:
摘要：
THE PRESENT INVENTION RELATES TO GENE THERAPY FOR THE TREATMENT OF TUMORS. ACCORDINGLY, THE PRESENT INVENTION DISCLOSES RECOMBINANT VECTOR EXPRESSION CONSTRUCTS (VECTORS) WHICH CONFER INFECTIVITY, REPLICATION, TRANSCRIPTION, OR ANY COMBINATION THEREOF WHEN THE CONSTRUCT IS INTRODUCED INTO CELLS EITHER IN VITRO OR IN VIVO, WITH OR WITHOUT A VIRAL PARTICLE. THE RECOMBINANT VECTOR CONSTRUCT IS ENGINEERED TO EXPRESS A COMBINATION OF TWO HETEROLOGOUS NUCLEOTIDE SEQUENCE(S), ESPECIALLY GENES ENCODING AN INFECTIOUS BURSAL DISEASE POLYPEPTIDE (VP2) COMBINED WITH ANOTHER NUCLEIC ACID MOLECULE ENCODING A CHICKEN ANEMIA VIRUS POLYPEPTIDE (VP3) OR MURINE ENDOSTATIN. FIGURE 1
