Michele Pagano,Jeffrey R. Skaar,Angelo Peschiaroli,N. Valerio Dorrello
申请号:
US13247488
公开号:
US20120157507A1
申请日:
2011.09.28
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to USP47 (ubiquitin specific protease 47) inhibitors and methods for inducing apoptosis or cell death in a target cell. In certain embodiments, the invention relates to methods and kits to screen for related agents that induce apoptosis. Additionally, the invention relates to assays for screening compounds capable of acting as USP47 inhibitors.