Thomas R. Alessi;Stan Lam;Michael A. DesJardin;Pauline C. Zamora;Scott D. Lautenbach
发明人:
Thomas R. Alessi,Michael A. DesJardin,Stan Lam,Scott D. Lautenbach,Pauline C. Zamora
申请号：
US12930950
公开号：
US08801700B2
申请日:
2011.01.19
申请国别(地区):
US
年份:
2014
代理人:
摘要：
An osmotic delivery system is disclosed for delivering an active agent formulation to a fluid environment. The osmotic delivery system typically comprises a reservoir having a lumen that contains the active agent formulation and an osmotic agent formulation and a piston assembly positioned in the lumen to isolate the active agent formulation from the osmotic agent formulation. The piston assembly typically comprises a body constructed and arranged for positioning in the lumen. The body is typically made of a polymeric material that is, for example, resistant to leaching in an organic solvent. In one embodiment, the body is a columnar body having a rim at a distal end thereof for engaging and sealing against a wall of the reservoir and the piston assembly further comprises a spring retained at the distal end of the columnar body for biasing the rim of the columnar body against the wall of the reservoir.
