Disclosed is a manufacturing method of wound covering material using a biopolymer. The wound covering material produced by the present invention can have a superior wound infection inhibitory effect and an effect of preventing adhesion. The manufacturing method of wound covering material for inhibiting wound infection and preventing adhesion comprises the following steps of: producing a solution using antibiotics, hyaluronic acid, or salts thereof； freezing the produced solution while rotating the solution； and drying the frozen solution.바이오폴리머를 이용한 창상 피복재의 제조방법을 개시한다. 본 발명에 따라 제조된 창상 피복재는 우수한 창상감염 억제 효과 및 유착 방지 효과를 가질 수 있다.
