System for handling tissue, the system comprising: an access cannula (18) having a distal end (21) to position itself in the tissue； an orientable assembly (20) comprising an orientable instrument (22) and a deformable conduit (24), the orientable instrument (22) being able to be at least partially disposed in the deformable conduit (24), the orientable instrument (22) comprising a control element (54) and a deflectable part (48) functionally connected to the control element (54), the orientable instrument (22) being able to adopt at least a substantially straight configuration and a curved configuration when the deflectable part (48) protrudes from the distal end (21) of the access cannula (18)； and wherein the orientable instrument (22) is operable to move the deflectable part (48) of the orientable instrument (22) away from a longitudinal axis (A) of the access cannula (18) in order to deform the conduit ( 24) deformable so that the deformable conduit (24) occupies a deformed position； characterized in that the orientable instrument (22) can be removably disposed in the deformable conduit (24) to allow removal of the deflectable part (48) of the orientable instrument (22) from the deformable conduit (24) without substantially displacing the position deformable duct (24) deformable after deformation.Sistema para manipular tejido, comprendiendo el sistema: una cánula (18) de acceso que presenta un extremo distal (21) para posicionarse en el tejido； un conjunto orientable (20) que comprende un instrumento orientable (22) y un conducto (24) deformable, pudiendo el instrumento orientable (22) ser por lo menos parcialmente dispuesto en el conducto (24) deformable, comprendiendo el instrumento orientable (22) un elemento de control (54) y una parte deflectable (48) conectada funcionalmente al elemento de control (54), pudiendo el instrumento orientable (22) adoptar por lo menos una configuración sustancialmente recta y una configuración curvada cuando la parte deflectab
