William D. THOMAS, JR.,Paul J. GIANNASCA,Zhenxi ZHANG,Wende LEI,Thomas P. MONATH
申请号：
US14512216
公开号：
US20150030612A1
申请日:
2014.10.10
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The invention provides active and passive immunization methods for preventing and treating Clostridium difficile infection, which involve percutaneous administration of C. difficile toxin-neutralizing polyclonal immune globulin, C. difficile toxoids, or combinations thereof. Also provided by the invention are C. difficile toxoids, C. difficile toxin-neutralizing polyclonal immune globulin, and methods of identifying subjects that produce C. difficile toxin-neutralizing polyclonal immune globulin.
