PROBLEM TO BE SOLVED: To provide novel agents that exert excellent effects on maintaining the function of stem cells, especially mesenchymal stem cells, and consist of natural product-derived components with excellent biosafety.SOLUTION: Provided is a stem cell function maintenance agent for maintaining the function of a mesenchymal stem cell by suppressing oxidative damage to the mesenchymal stem cells, the agent containing as an active ingredient extract of one or more plants or hydrolysates thereof, which are selected from the group consisting of Luffa cylindrical, Prunus persica, Glycine max, Callicarpa japonica Thunb., Prunus armeniaca, and Alchemilla vulgaris.SELECTED DRAWING: NoneCOPYRIGHT: (C)2020,JPO&INPIT【課題】幹細胞、特に間葉系幹細胞の機能維持にすぐれた効果を発揮し、かつ生体安全性にすぐれた天然物由来成分からなる新規な剤の提供。【解決手段】ヘチマ、モモ、ダイズ、ムラサキシキブ、アンズ、ハゴロモグサからなる群より選択される1又は2以上の植物の抽出物又はその加水分解物を有効成分として含有し、間葉系幹細胞の酸化ダメージを抑制して、当該間葉系幹細胞の機能を維持する幹細胞機能維持剤。【選択図】なし