The present invention relates to a novel and stable levothyroxine sodium pharmaceutical composition and belongs to the technical field of pharmaceutical preparation and in particular to a levothyroxine sodium tablets. In the current invention, the levothyroxine sodium dosage forms comprise as active ingredient levothyroxine sodium in an amount of about 0.01% w/w to about 1% w/w and as excipients Microcrystalline cellulose in an amount of 80% w/w to 95% w/w , disintegrant in an amount of 5% w/w to 10% w/w , glidant in an amount of 0.5% w/w to 3% w/w , and lubricant in an amount of 0.5% w/w to 2% w/w .The proposed composition by improving the stability and the dissolution of the preparation can benefit the clinical application.Finally, the present invention is directed to therapeutic agents for treatment of hormone disorders and relates to stable pharmaceutical dosage forms of Levothyroxine sodium.
