PURPOSE: A pharmaceutical composition for suppressing neural cell apoptosis or neurodegeneration is provided to effectively prevent or treat neurodegenerative diseases.CONSTITUTION: A pharmaceutical composition for suppressing neural cell apoptosis or neurodegeneration contains therapeutically effective amount of substituted azole derivative compounds of chemical formula I pharmaceutically acceptable salt, isomer, solvate, hydrate, or mixture thereof and pharmaceutically acceptable carrier. The pharmaceutical composition is used for treating diseases related to neural cell apoptosis or neurodegeneration by contacting an object.COPYRIGHT KIPO 2012신경 세포 사멸 또는 신경 퇴화를 억제하기 위한 약학적 조성물에 관한 것이다. 일 구체예에 따른 약학적 조성물에 의하면, 신경 세포 사멸 또는 신경 퇴화와 관련된 질환을 효과적으로 예방 또는 치료할 수 있다.