Research Institute at Nationwide Children's Hospital
发明人:
Lauren O. Bakaletz,Steven D. Goodman
申请号：
US16475654
公开号：
US20190338018A1
申请日:
2018.01.03
申请国别(地区):
US
年份:
2019
代理人:
摘要：
This disclosure provides antibody fragments and isolated polypeptides comprising the antibody fragments that are useful as a therapeutic for those with an existing infection characterized by the formation of biofilms. Antibody fragments and isolated polypeptides comprising the antibody fragments can be administered to detect, treat, or prevent infection and/or remediate biofilms. Bacteria that cannot form functional biofilms are more readily cleared by the remainder of the host's immune system and/or traditional antibiotics.
