N-PHENYLPIPERAZINE DERIVATIVES THAT ARE ANTAGONISTS OF A1A, A1D ADRENOCEPTORS AND 5-HT1A RECEPTORS FOR THE TREATMENT OF BENIGN PROSTATE HYPERPLASIA, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME
UNIVERSIDADE FEDERAL DO RIO DE JANEIRO-UFRJ;UNIÃO BRASILIENSE DE EDUCAÇÃO E CULTURA - UBEC
发明人:
Claudia Lucia Martins Da Silva,Fernanda Chagas Da Silva,Luana Chaves Barberato,Luciana De Camargo Nascente,Jessica Barbosa Do Nascimento Viana,Renata Oliveira Silva,Laís Flávia Nunes Lemes,François Ge
申请号：
US14370646
公开号：
US20150011566A1
申请日:
2013.01.04
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The present invention provides N-phenylpiperazine derivatives for use as multiple binders and/or antagonists of α1A adrenoceptors, α1D adrenoceptors and 5-HT1A serotonin receptors. These substances are candidates to prototypes for the treatment of benign prostate hyperplasia and lower urinary tract symptoms, and are useful in pharmaceutical compositions.
