Rachel Meyers;Akshay Vaishnaw;Sayda Elbashir;Saraswathy V. Nochur;Muthiah Manoharan
发明人:
Akshay Vaishnaw,Saraswathy V. Nochur,Sayda Elbashir,Muthiah Manoharan,Rachel Meyers
申请号:
US13359421
公开号:
US20120189555A1
申请日:
2012.01.26
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Methods and compositions are provided for the prevention or treatment of RSV infection in a human. The methods include administering one or more doses of a composition comprising an siRNA. The dose can be formulated for topical or parenteral administration. Topical administration includes administration as a nasal spray, or by inhalation of respirable particles or droplets. The siRNA comprises a sense strand of ALN-RSV01 and an antisense strand of ALN-RSV01.