The invention relates to medicine and to cosmetology. The dispersion of solid lipid nano-particles and compositions on the basis thereof are intended for cosmetic purposes: enhanced moisturizing, nourishing and increasing the elasticity of sensitive skin, and for pharmaceutical purposes: treating atopic dermatitis and eczema with the aid of the solid lipid nano-particles, which include moisturizing substances and biologically active substances (BAS). The dispersion of solid lipid nano-particles with a size of 50 to 300 nm for cosmetic agents comprises cosmetic wax, an ultraviolet filter, decyl glucoside, vegetable oil, pentyleneglycol and purified water. A corticosteroid is additionally introduced into the dispersion for treating atopic dermatitis and eczema. The cosmetic compositions comprise a dispersion of solid lipid nano-particles with a size of 50 to 300 nm as a biologically active additive, and the base includes propyleneglycol extracts of medicinal plants, vegetable oil, D-pantenol, a cross-linking agent, a preservative, an emulsifier and purified water for intensive moisturizing and nourishment of the skin. The pharmaceutical compositions comprise a dispersion of solid lipid nano-particles with a size of 50 to 300 nm as a biologically active additive, said dispersion being analogous to cosmetic agents containing a corticosteroid.L'invention se rapporte au domaine de la médecine et de la cosmétologie, et concerne une dispersion de nanoparticules de lipides solides et une composition la comprenant, lesquelles peuvent être utilisées à des fins cosmétiques, comme l'hydratation accrue, la nutrition et l'augmentation de l'élasticité de la peau sensible, ainsi qu'à des fins pharmaceutiques afin de traiter une dermatite atopique et l'exéma à l'aide de nanoparticules de lipides solides comprenant des substances hydratantes bioactives. La dispersion de nanoparticules de lipides solides pour agents cosmétiques et d'un diamètre de 50 à 300 nm comprend de la cire cosmé