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Substituted 3-(biphenyl-3-yl)-8,8-difluoro-4-hydroxy-1-azaspiro[4.5]dec-3-en-2-ones for therapy
专利权人:
Ningshu Liu
发明人:
Ningshu Liu,Kai Thede,Ursula Mönning,Arne Scholz,Christoph-Stephan Hilger,Ulf Bömer,Reiner Fischer
申请号:
US13985940
公开号:
US09000026B2
申请日:
2012.02.14
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The invention relates to substituted 3-(biphenyl-3-yl)-8,8-difluoro-4-hydroxy-1-azaspiro[4.5]dec-3-en-2-ones of the formula (Ia) for therapeutic purposes, to pharmaceutical compositions and to their use in therapy, in particular for the prophylaxis and therapy of tumor disorders.The invention also relates to novel compounds of the formula (I)in which W, X, Y, Z, A, B, D and G have the meanings given above,to a plurality of processes and intermediates for their preparation, and to their use as pesticides and/or herbicides and/or fungicides.The invention also relates to selectively herbicidal compositions comprising, firstly, the halogen-substituted spirocyclic ketoenols and, secondly, a crop plant compatibility-improving compound.The present invention furthermore relates to the boosting of the action of crop protection compositions comprising, in particular, halogen-substituted spirocyclic ketoenols, through the addition of ammonium salts or phosphonium salts and optionally penetrants, to the corresponding compositions, to processes for producing them and to their application in crop protection as pesticides and/or fungicides and/or for preventing unwanted plant growth.
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