Surgical clip appliers are provided including a clip carrier disposed within a channel assembly and defining a channel and a plurality of windows therein a plurality of clips slidably disposed within said channel of said clip carrier a wedge plate reciprocally disposed within said channel assembly, said wedge plate including a plurality of apertures formed along a length thereof and a clip follower slidably disposed within said channel of said clip carrier and disposed proximally of said plurality of clips, said clip follower being configured and adapted for selective engagement with said windows of said clip carrier and said apertures of said wedge plate. The clip follower is configured and adapted to urge said plurality of clips, in a distal direction relative to said clip carrier, upon reciprocal movement of said wedge plate. The clip applier may be adapted to different size clips by the method of replacing modular components.
