Drug conjugate composition

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专利权人:

ImmunoGen; Inc.

发明人:

Amphlett, Godfrey,Zhang, Wei,Fleming, Michael,Chih, Hung-Wei

申请号：

AU2011201150

公开号：

AU2011201150B2

申请日:

2011.03.15

申请国别(地区):

AU

年份:

2013

代理人:

摘要：

#$%^&*AU2011201150B220131010.pdf#####ABSTRACT The invention provides a liquid composition and a Iyophilized composition comprising a therapeutically effective amount of a conjugate comprising an antibody 5 chemically coupled to a maytansinoid. The invention further provides a method for killing a cell in a human comprising administering to the human either of the compositions such that the antibody binds to the surface of the cell and the cytotoxicity of the maytansinoid is activated, whereby the cell is killed.

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