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Aqueous topical gel of high stability based on metronidazole and method of preparation
专利权人:
GALDERMA S.A.
发明人:
BRZOKEWICZ, ALAIN,PEDRASSI, GERALD,ZARIF, LEILA
申请号:
AU2006218043
公开号:
AU2006218043B2
申请日:
2006.02.16
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
The present invention relates to a method for preparing an aqueous gel based on metronidazole, comprising the successive steps consisting in: (A) forming a solvent medium M comprising water and propylene glycol; (B) dissolving the metronidazole in this solvent medium M, and optionally diluting the medium obtained by addition of water, whereby a solution S of metronidazole is obtained; and then (C) mixing the solution S obtained with a gelling polymer, in a sufficient quantity to ensure gelling of the composition. The invention also relates to the aqueous gels of high stability which may be obtained according to this method, and the use of these gels as dermatological compositions .
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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