MEMORIAL SLOAN KETTERING CANCER CENTER;EUREKA THERAPEUTICS, INC.
发明人:
Renier J. Brentjens,Eric L. SMITH,Cheng LIU
申请号：
US15613638
公开号：
US20180360880A1
申请日:
2018.01.19
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The presently disclosed subject matter provides for methods and compositions for treating multiple myeloma. It relates to chimeric antigen receptors (CARs) that specifically target B cell maturation antigen (BMCA), and immunoresponsive cells comprising such CARs. The presently disclosed BMCA-specific CARs have enhanced immune-activating properties, including anti-tumor activity.
