A wound protecting and fixing device comprises at least one opening-comprising protecting and fixing layer (1). The opening-comprising protecting and fixing layer (1) is longitudinally provided with an opening (11) in communication with upper and lower end surfaces thereof. The opening (11) surrounds the wound therein, so that the opening-comprising protecting and fixing layer (1) can limit the increase of the tension of the wound and movement-incurred wrinkles of the skin at the wound. The opening-comprising protecting and fixing layer (1) may have a flexible opening protecting and fixing layer (1a) and a rigid opening protecting and fixing layer (1b). The wound protecting and fixing device can prevent the wound from being torn open or splitting, prevent wrinkles incurred by the movement of the skin at the wound, and prevent damages incurred by relative displacement and friction between the wound, the dressing, and the infusion catheter to the wound.
