Lin Mei,Wen-Cheng Xiong,Cheng-Yong Shen,Yan-Mei Tao,Shi-Wen Luo
申请号：
US14188318
公开号：
US09493542B2
申请日:
2014.02.24
申请国别(地区):
US
年份:
2016
代理人:
摘要：
Compositions that inhibit or block the interaction between Erbin and ErbB2 and methods of their use are provided. Preferred compositions include peptides that inhibit or block Erbin and ErbB2 interaction under physiologic conditions in a subject. One embodiment provides an isolated peptide fragment of ErbB2 including the C-terminal 15 amino acids of ErbB2. The peptide fragment can be about 15 to 27 amino acids in length.
