A system for generating medical image scanner configurations includes a scanner configuration database and a simulation component. The database stores a scanner configuration dataset corresponding to a medical image scanner. The simulation component includes a display module which is configured to present a graphical user interface (GUI) utilized by the medical image scanner, and an editing module which is configured to create a modified scanner configuration dataset based on commands received from a user via the GUI. Additionally, the simulation component includes a simulation module which is configured to (i) perform a simulation of the medical image scanner using the modified scanner configuration dataset to yield simulated results, (ii) use the display module to present the simulated results in the GUI, and (iii) in response to receiving user approval of the simulated results via the GUI, save the modified scanner configuration dataset to the database.