BARBARA BRANNETTI,JENNIFER BROGDON,Boris ENGELS,BRIAN GRANDA,LU HUANG,MING LEI,NA LI,JIMIN ZHANG
申请号：
IN201714035545
公开号：
IN201714035545A
申请日:
2017.10.06
申请国别(地区):
IN
年份:
2018
代理人:
摘要：
The invention provides compositions and methods for treating diseases associated with expression of CD20 or CD22. The invention also relates to chimeric antigen receptor (CAR) specific to CD20 or CD22, vectors encoding the same, and recombinant T or natural killer (NK) cells comprising the CD20 CAR or CD22 CAR. The invention also includes methods of administering a genetically modified T cell or NK cell expressing a CAR that comprises a CD20 or CD22 binding domain.
