There is provided herein N4- (4- ([1,2,4] triazol [1,5-a] pyridin-7-yl oxygroup) -3- aminomethyl phenyl)-N6- (4,Dimethyl -4 4-,5- bis- Hydrogen oxazole -2- base) quinazoline -4,The method of the solid-state Fen San Body of 6- diamines He solid-state Fen San Body described in System Prepare. In addition, there is provided herein comprising N4- (4- ([1,2,4] triazol [1,5-a] pyridin-7-yl oxygroup) -3- aminomethyl phenyl)-N6- (4,Dimethyl -4 4-,5- bis- Hydrogen oxazole -2- base) quinazoline -4,The Drug Wu Group of the solid-state Fen San Body of 6- diamines closes object and application thereof.本文提供了N4‑(4‑([1,2,4]三唑并[1,5‑a]吡啶‑7‑基氧基)‑3‑甲基苯基)‑N6‑(4,4‑二甲基‑4,5‑二氫噁唑‑2‑基)喹唑啉‑4,6‑二胺的固態分散體和製備所述固態分散體的方法。另外,本文提供了包含N4‑(4‑([1,2,4]三唑并[1,5‑a]吡啶‑7‑基氧基)‑3‑甲基苯基)‑N6‑(4,4‑二甲基‑4,5‑二氫噁唑‑2‑基)喹唑啉‑4,6‑二胺的固態分散體的藥物組合物及其用途。