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COMPOSÉS AMPHIPHILES BISCATIONIQUES ET TRISCATIONIQUES UTILISÉS COMME AGENTS ANTIMICROBIENS
专利权人:
Temple University Of The Commonwealth System Of Higher Education;Villanova University
发明人:
申请号:
EP14860208.9
公开号:
EP3065547A4
申请日:
2014.11.05
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
The present disclosure provides an antimicrobial composition including a compound which is a biscationic or triscationic amphiphile, and the method of making such an antimicrobial composition, and the method of using such a compound or composition for antimicrobial use. The antimicrobial composition can include a compound having the formula (I) wherein R is a methylene group unsubstituted or optionally substituted, s is an integer in the range from 1 to 6, R1, R2, R3 or R4 is H or a C 1-4 alkyl unsubstituted or optionally substituted, X is a halogen, m and n are integers in the range from 5 to 25, and m is not equal to n. Alternatively, the antimicrobial composition can comprise a compound having the formula (III) or (IV) wherein R1, R2, R3, R4 R5, or R6 is H or a C1-4 alkyl unsubstituted or optionally substituted, X or Y is a halogen, and m and n are integers in the range from 5 to 25.
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