The compound of formula (I) ** Formula ** or a pharmaceutically acceptable salt thereof, wherein X is selected from the group consisting of O and S； And it is selected from the group consisting of O and S； Z is selected from the group consisting of Z1, Z2, Z3 and Z4, where Z1 is ** Formula ** Z2 is ** Formula ** Z3 is ** Formula ** and Z4 is ** Formula ** with the condition that Z is only Z4 when at least one of X or Y is S； R1 is selected from the group consisting of hydrogen, (C1-C6) alkyl, cycloalkyl (C3-C7), haloalkyl (C1-C6), unsubstituted arylalkyl (C1-C4), substituted (C1-C6) arylalkyl, (C1-C6) heteroalkyl, substituted or unsubstituted aryl and substituted or unsubstituted heteroaryl； R2 is selected from the group consisting of hydrogen, halogen, cyano and (C1-C6) alkoxy； R3 is selected from the group consisting of hydrogen, halogen, (C1-C6) alkyl, halo (C1-C6) alkyl, (C1-C6) alkoxy, cyano and N, N-dimethylamino； R4 is selected from the group consisting of tetrazol, oxadiazolone, thiadiazolone, methylsulfonylcarbamoyl and N-hydroxycarbamoyl； and R5 is selected from the group consisting of carboxy, tetrazol, oxadiazolone, thiadiazolone, methylsulfonylcarbamoyl and N-hydroxycarbamoyl.El compuesto de formula (I)**Fórmula** o una sal farmaceuticamente aceptable del mismo, en la que X se selecciona de entre el grupo que consiste en O y S； Y se selecciona de entre el grupo que consiste en O y S； Z se selecciona de entre el grupo que consiste en Z1, Z2, Z3 y Z4, en donde Z1 es**Fórmula** Z2 es**Fórmula** Z3 es**Fórmula** y Z4 es**Fórmula** con la condicion de que Z unicamente es Z4 cuando al menos uno de X o Y es S； R1 se selecciona de entre el grupo que consiste en hidrogeno, alquilo (C1-C6), cicloalquilo (C3-C7), haloalquilo (C1-C6), arilalquilo (C1-C4) no sustituido, arilalquilo (C1-C6) sustituido, heteroalquilo (C1-C6), arilo sustituido o no sustituido y heteroarilo sustituido o no sustituido； R2 se selecciona de entre el grupo que consiste en hidrogeno, halogen
