TOLEROGENIC SYNTHETIC NANOCARRIERS FOR INDUCING REGULATORY B CELLS

• 收藏
• 分享

专利权人:

Selecta Biosciences; Inc.

发明人:

Maldonado, Roberto A.

申请号：

AU2017225163

公开号：

AU2017225163A1

申请日:

2017.09.11

申请国别(地区):

AU

年份:

2017

代理人:

摘要：

#$%^&*AU2017225163A120171005.pdf#####ABSTRACT Disclosed are synthetic nanocarrier methods, and related compositions, comprising B cell and/or MHC Class II-restricted epitopes and immunosuppressants in order to generate tolerogenic immune responses, such as the generation of antigen-specific regulatory B cells. See Fig. 2.WO 2012/149301 PCT/US2012/035431 1/2 CD3 CD5FOXP3 mphocyte' 8.60 53 L(1L _____________ SC/SSC CD3 CD25 gated FSC CD3 CD25 CID4 Fig. 1 o CD24+CVA- ILl 0+ TGFb± 40- 9 CD24+OVA+ ILI 0+ IGFb+ 0 CD24-OVA± ILl 0+ IGFb+ o CD24-OVA- ILI 0+ TGFb+ S300 4u10 00 0--~ 'yI T 0 ) Lf~ 0 Fi.m STTRTTTTT S-RTCRTTL ?6

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/