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COMPOSITION VECTRICE POUR LE TRANSPORT D'UN ACIDE NUCLEIQUE
专利权人:
LTD.;OTSUKA PHARMACEUTICAL CO.
发明人:
TOYOBUKU, HIDEKAZU,MIYAO, HIDEO,SATO, MASAKO,SEKIGUCHI, KAZUO
申请号:
EP06811872
公开号:
EP1946761A4
申请日:
2006.10.17
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
An object of the present invention is to provide a nucleic acid delivery carrier composition of low toxicity and high safety, the carrier composition, when used to administer a nucleic acid such as an siRNA into an animal-derived cell or organism, being capable of delivering efficiently the nucleic acids into the cells while protecting it from being degraded; and a nucleic acid deliver composition containing the carrier and a nucleic acid. The carrier composition for delivery of a nucleic acid is prepared by mixing (A) a cationic lipid having a steroid skeleton with (B) a tertiary ammonium salt-type cationic lipid. The nucleic acid delivery composition is prepared by mixing the nucleic acid delivery carrier with a nucleic acid.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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