The disclosure relates to a method of reprogramming one or more somatic cells,e.g., partially differentiated orfully/terminally differentiated somatic cells, to a less differentiated state,e.g., a pluripotent or multipotent state. In further embodimentsthe invention also relates to reprogrammed somatic cells produced by methodsof the invention, to chimeric animals comprisingreprogrammed somatic cells of the invention, to uses of said cells, and tomethods for identifying agents useful for reprogrammingsomatic cells.
