Commonwealth Scientific and Industrial Research Organisation
发明人:
Graham, Michael Wayne,Rice, Robert Norman,Waterhouse, Peter Michael,Wang, MingBo
申请号:
EP20070008204
公开号:
EP1857549(B1)
申请日:
1999.03.19
申请国别(地区):
欧洲专利局
年份:
2018
代理人:
摘要:
The present invention relates generally to a method of modifying gene expression and to synthetic genes for modifying endogenous gene expression in a cell, tissue or organ of a transgenic organism, in particular a transgenic animal or plant. More particularly, the present invention utilises recombinant DNA technology to post-transcriptionally modify or modulate the expression of a target gene in a cell, tissue, organ or whole organism, thereby producing novel phenotypes. Novel synthetic genes and genetic constructs which are capable or repressing delaying or otherwise reducing the expression of an endogenous gene or a target gene in an organism when introduced thereto are also provided.