PURPOSE: A surface modification of the polymer support for the stem cell transplantation using the extracellular matrix which is decellularization is provided to efficiently facilitate the attach of a cell and the polymer support which is surface modified is effective for the growth and specialization of the stem cell. CONSTITUTION: A surface modification of the polymer support for the stem cell transplantation using the extracellular matrix which is decellularization is as follows. The porosity complex support material is provided through foaming and freezing procedure. It transplants histiocyte within the complex support material and cultivates, and this is dipped in the decellularization solution and decellularizes after the manufactured porosity complex support material. The stem cell to the supporter is transformed in decellularization.본 발명은 탈세포화된 세포외 기질을 이용한 줄기세포 이식용 고분자 지지체의 표면 개질 방법에 관한 것이다. 본 발명에 따른 고분자 지지체의 표면 개질 방법은 특정세포로부터 유래된 탈세포화된 세포외 기질을 이용하여 지지체 표면을 개질함으로써, 세포부착을 용이하게 하고 나아가 줄기세포의 성장 및 분화에도 효과적인 생체모방형의 표면 환경을 구현할 수 있다.