Mohammad HARIS,Anup SINGH,Kejia CAI,Ravinder REDDY,Feliks KOGAN,Ravi PRAKASH REDDY NANGA,Hari HARIHARAN
申请号：
US14781441
公开号：
US20160041245A1
申请日:
2014.04.04
申请国别(地区):
US
年份:
2016
代理人:
摘要：
A non-invasive imaging approach using CEST and MRS may be used to monitor the cleavage of the poly-L-glutamate (PLG) backbone. The cleavage of PLG by cathespsin B can expose exchangeable —NH2 protons in the PLG that are then monitored non-invasively through CEST. The technique can provide direct information on malignant tissue and tumor aggressiveness, and can also be used to monitor treatment.
