The invention provides for a device (100) for use in electrical nerve modulation in a subject, characterized in that it comprises a rotational and linear actuator (110)； a tubular element (101) having a proximal end connected to the actuator (110) and a distal end； a flexible shaft (102) coaxially disposed within the tubular element (101), comprising a proximal end operably connected to the actuator (110) and a distal end, and adapted to be slid along the tubular element (101)； a conformable support (103) comprising a proximal end operably connected to the tubular element's (101) distal end, and a distal end operably connected to the flexible shaft's (102) distal end, having a portion of its length helically wrapped about a distal portion of the flexible shaft (102) so to define a pitch (500) and a radius (400)； and a plurality of electrodes (104) operably disposed along the helically configured portion of the conformable support (103), and electrically connectable to a generator (200), adapted to contact the endoluminal surface of a blood vessel of the subject and deliver electrical energy； wherein the pitch (500), radius (400) or both of the helically configured portion of the conformable support (103) can be modified via actuator's (110) driven extension, retraction and/or rotation of the flexible shaft (102).
