您的位置: 首页 > 农业专利 > 详情页

FORMULATION DE SUSPENSION POUR LE TRAITEMENT DE LA TUBERCULOSE
专利权人:
Universitat de Barcelona
发明人:
申请号:
EP18382385.5
公开号:
EP3578167A1
申请日:
2018.06.04
申请国别(地区):
EP
年份:
2019
代理人:
摘要:
Kit of products for extemporaneous preparation of an oily suspension formulation comprising: (i) a dry powder composition of anti-tuberculosis effective amounts of the active pharmaceutical ingredients (APIs): isoniazid, rifampicin and pyrazinamide; and (ii) an oily liquid dispersing medium for reaching a predetermined volume of the suspension formulation, comprising: adequate amounts of the dispersing agents: ethoxylated hydrogenated castor oil, simethicone, and dichlorodimethylsilane-treated silica; adequate amounts of one or more flavoring agents; and the amount of medium-chain triglycerides, as oily base, that is necessary for reaching the predetermined volume of the suspension formulation; wherein (i) and (ii) are packaged in physically separated containers, arranged to be mixed extemporaneously to form the suspension formulation. The formulation is stable for more than three weeks under fridge conditions, and it is useful as a first-line treatment of tuberculosis in humans, particularly in children, with easy dose control, little effort, and good adherence.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充