David Vaux,Letitia Dean,Stephen Davies,Angela Russell,Graham Wynne,Carole Bataille,Méabh Brennan
申请号:
US15121973
公开号:
US20170008849A1
申请日:
2015.02.27
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention relates to quinoline compounds as defined by Formula I below. Such quinoline compounds have been shown to inhibit the formation of amyloid deposits (e.g., amyloid oligomers, fibrils or plaques). Consequently, these compounds are suitable for treating a range of diseases and disorders in which amyloid deposits are implicated, such as type-2 diabetes and Alzheimers disease.