INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property 1111111111111111111111111111111111111111111111111111111011110111111111110111111 Organization International Bureau (10) International Publication Number (43) International Publication Date ......0\" WO 2018/002238 Al 04 January 2018 (04.01.2018) W I PO I PCT (51) International Patent Classification: MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, A61K 35/744 (2015.01) A23L 33/00 (2016.01) TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, A61K 35/745 (2015.01) A61P 25/22 (2006.01) KM, ML, MR, NE, SN, TD, TG). A61K 35/747 (2015.01) (21) International Application Number: Declarations under Rule 4.17: PCT/EP2017/066158 — as to applicants entitlement to apply for and be granted a patent (Rule 4.17(ii)) (22) International Filing Date: — as to the applicants entitlement to claim the priority of the 29 June 2017 (29.06.2017) earlier application (Rule 4.17(iii)) — of inventorship (Rule 4.17(iv)) (25) Filing Language: English (26) Publication Language: English Published: — with international search report (Art. 21(3)) (30) Priority Data: 16177649.7 01 July 2016 (01.07.2016) EP (71) Applicant: NESTEC S.A. [CH/CH] Av. Nestle 55, 1800 Vevey (CH). (72) Inventors: BLANCHARD, Carine Chemin de Longeraie 50, 1052 Le Mont-sur-Lausanne (CH). MITCHELL, _ Ellen, Siobhan 109 Grandview Ave, White Plains, NY New York 10605 (US). NEMBRINI, Chiara 34, Route de — = Palezieux, 1610 Oron-La-Ville Vaud (CH). SCHNEIDER, Nora Rte de la Croix-Blanche 31, 1066 Epalinges Vaud = (CH). = (74) Agent: NAUDE, Dawn Centre de Recherche Nestle, Case _ — postale 44, Vers-chez-les-Blanc, 1000 Lausanne 26 (CH). = (81) Designated States (unless otherwise indicated, for every = kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, = CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, = DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID,